Wilson, V S

The contribution of hepatic inactivation of testosterone to the lowering of serum testosterone levels by ketoconazole. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Mar 2000 - 128-37 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1096-6080

10.1093/toxsci/54.1.128 doi


Animals
Antifungal Agents--pharmacology
Aryl Hydrocarbon Hydroxylases
Biotransformation
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--metabolism
Cytosol--drug effects
Electrophoresis, Polyacrylamide Gel
Glucuronosyltransferase--metabolism
Immunoblotting
Ketoconazole--pharmacology
Liver--drug effects
Male
Mice
Microsomes, Liver--drug effects
Steroid Hydroxylases--antagonists & inhibitors
Sulfotransferases--metabolism
Testis--drug effects
Testosterone--blood
Time Factors