Signal transduction cascade in staurosporine-induced prostaglandin E(2) production by rat peritoneal macrophages. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Apr 2000
- 206-13 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
Animals Arachidonic Acid--metabolism Blotting, Western Cell Survival--drug effects Cells, Cultured Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors--pharmacology Dinoprostone--biosynthesis Enzyme Inhibitors--pharmacology Isoenzymes--biosynthesis Kinetics Macrophages, Peritoneal--drug effects Male Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases--antagonists & inhibitors Phosphatidylinositol 3-Kinases--metabolism Phosphoinositide-3 Kinase Inhibitors Phospholipases A--metabolism Phosphorylation Prostaglandin-Endoperoxide Synthases--biosynthesis Protein Kinase C--antagonists & inhibitors Rats Rats, Sprague-Dawley Signal Transduction--drug effects Staurosporine--pharmacology