Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Apr 2000
- 48-59 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
Animals Apoptosis--drug effects Blotting, Western Caspase 3 Caspases--analysis Cell Line Cycloheximide--pharmacology Cytochrome c Group--metabolism Cytosol--drug effects DNA Fragmentation--drug effects Electrophoresis Enzyme Precursors--analysis HL-60 Cells Humans Jurkat Cells Liver--cytology NF-kappa B--genetics Oxazepines--pharmacology Oxidative Stress--physiology Protein Synthesis Inhibitors--pharmacology Pyrroles--pharmacology Radioligand Assay Rats T-Lymphocytes--drug effects Up-Regulation--drug effects