TY - GEN AU - Nacro,K AU - Bienfait,B AU - Lee,J AU - Han,K C AU - Kang,J H AU - Benzaria,S AU - Lewin,N E AU - Bhattacharyya,D K AU - Blumberg,P M AU - Marquez,V E TI - Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C? SN - 0022-2623 PY - 2000///0413 KW - 4-Butyrolactone KW - analogs & derivatives KW - Antineoplastic Agents KW - chemical synthesis KW - Binding, Competitive KW - Crystallography, X-Ray KW - Drug Design KW - Drug Screening Assays, Antitumor KW - Enzyme Activation KW - Epidermal Growth Factor KW - antagonists & inhibitors KW - Isoenzymes KW - chemistry KW - Ligands KW - Models, Molecular KW - Protein Kinase C KW - Protein Kinase C-alpha KW - Stereoisomerism KW - Structure-Activity Relationship KW - Tumor Cells, Cultured KW - Valerates N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/jm9904607 ER -