Nacro, K <br/><br/>
Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?  [electronic resource] 

 -  Journal of medicinal chemistry  Mar 2000 
 - 921-44 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm9904607  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>4-Butyrolactone--analogs & derivatives<br/>Antineoplastic Agents--chemical synthesis<br/>Binding, Competitive<br/>Crystallography, X-Ray<br/>Drug Design<br/>Drug Screening Assays, Antitumor<br/>Enzyme Activation<br/>Epidermal Growth Factor--antagonists & inhibitors<br/>Isoenzymes--chemistry<br/>Ligands<br/>Models, Molecular<br/>Protein Kinase C--chemistry<br/>Protein Kinase C-alpha<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Tumor Cells, Cultured<br/>Valerates--chemical synthesis