TY - GEN AU - Helgason,C D AU - Kalberer,C P AU - Damen,J E AU - Chappel,S M AU - Pineault,N AU - Krystal,G AU - Humphries,R K TI - A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice SN - 0022-1007 PY - 2000///0404 KW - Animals KW - Apoptosis KW - B-Lymphocytes KW - immunology KW - Bone Marrow Cells KW - Bone Marrow Transplantation KW - Cell Cycle KW - Ficoll KW - analogs & derivatives KW - Flow Cytometry KW - Immunity, Cellular KW - Immunoglobulin M KW - Lymph Nodes KW - cytology KW - Mice KW - Mice, Inbred NOD KW - Mice, Mutant Strains KW - Mice, SCID KW - Mitogen-Activated Protein Kinases KW - metabolism KW - Myeloproliferative Disorders KW - Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases KW - Phosphoric Monoester Hydrolases KW - Phosphorylation KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Receptors, Antigen, B-Cell KW - Signal Transduction KW - Spleen KW - Trinitrobenzenes KW - src Homology Domains N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1084/jem.191.5.781 ER -