A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice. [electronic resource]
- The Journal of experimental medicine Mar 2000
- 781-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-1007
10.1084/jem.191.5.781 doi
Animals Apoptosis B-Lymphocytes--immunology Bone Marrow Cells--immunology Bone Marrow Transplantation Cell Cycle Ficoll--analogs & derivatives Flow Cytometry Immunity, Cellular Immunoglobulin M Lymph Nodes--cytology Mice Mice, Inbred NOD Mice, Mutant Strains Mice, SCID Mitogen-Activated Protein Kinases--metabolism Myeloproliferative Disorders Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases Phosphoric Monoester Hydrolases--immunology Phosphorylation Protein Serine-Threonine Kinases Proto-Oncogene Proteins--metabolism Proto-Oncogene Proteins c-akt Receptors, Antigen, B-Cell Signal Transduction Spleen--cytology Trinitrobenzenes--immunology src Homology Domains--immunology