TY - GEN AU - Migita,K AU - Tanaka,H AU - Okamoto,K AU - Yoshikawa,N AU - Ichinose,Y AU - Urayama,S AU - Yamasaki,S AU - Ida,H AU - Kawabe,Y AU - Kawakami,A AU - Eguchi,K TI - FK506 augments glucocorticoid-mediated cyclooxygenase-2 down-regulation in human rheumatoid synovial fibroblasts SN - 0023-6837 PY - 2000///0316 KW - Arthritis, Rheumatoid KW - enzymology KW - Base Sequence KW - Cells, Cultured KW - Cyclooxygenase 2 KW - DNA Primers KW - Dexamethasone KW - pharmacology KW - Down-Regulation KW - drug effects KW - Fibroblasts KW - Fluorescent Antibody Technique, Indirect KW - Humans KW - Isoenzymes KW - genetics KW - Membrane Proteins KW - NF-kappa B KW - metabolism KW - Promoter Regions, Genetic KW - Prostaglandin-Endoperoxide Synthases KW - RNA, Messenger KW - Receptors, Glucocorticoid KW - Reverse Transcriptase Polymerase Chain Reaction KW - Subcellular Fractions KW - Synovial Membrane KW - Tacrolimus KW - Transcription, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/labinvest.3780017 ER -