Popik, W <br/><br/>
Inhibition of CD3/CD28-mediated activation of the MEK/ERK signaling pathway represses replication of X4 but not R5 human immunodeficiency virus type 1 in peripheral blood CD4(+) T lymphocytes.  [electronic resource] 

 -  Journal of virology  Mar 2000 
 - 2558-66 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0022-538X 
<br/><br/><label>Standard No.: </label>10.1128/jvi.74.6.2558-2566.2000  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Biological Transport<br/>Butadienes--pharmacology<br/>CD28 Antigens--metabolism<br/>CD3 Complex--metabolism<br/>CD4 Antigens--metabolism<br/>CD4-Positive T-Lymphocytes--cytology<br/>Cell Nucleus--metabolism<br/>Cells, Cultured<br/>DNA, Viral--metabolism<br/>Down-Regulation<br/>Enzyme Activation<br/>Enzyme Inhibitors--pharmacology<br/>HIV-1--drug effects<br/>Humans<br/>MAP Kinase Signaling System<br/>Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors<br/>Nitriles--pharmacology<br/>Proviruses--genetics<br/>Receptors, CXCR4--metabolism<br/>Transcription, Genetic<br/>Virus Integration<br/>Virus Replication--drug effects