TY - GEN AU - Pierce,K L AU - Maudsley,S AU - Daaka,Y AU - Luttrell,L M AU - Lefkowitz,R J TI - Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors SN - 0027-8424 PY - 2000///0323 KW - Adrenergic alpha-Agonists KW - pharmacology KW - Animals KW - Brimonidine Tartrate KW - COS Cells KW - Clathrin KW - metabolism KW - Endocytosis KW - Enzyme Inhibitors KW - Epidermal Growth Factor KW - ErbB Receptors KW - Fluorescent Antibody Technique KW - GTP-Binding Proteins KW - Isoproterenol KW - Mitogen-Activated Protein Kinases KW - Phosphorylation KW - Quinazolines KW - Quinoxalines KW - Receptors, Adrenergic, alpha KW - Receptors, Adrenergic, beta KW - Receptors, Cell Surface KW - Transfection KW - Tyrphostins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.97.4.1489 ER -