TY - GEN AU - Chu,I AU - Favreau,L AU - Soares,T AU - Lin,C c AU - Nomeir,A A TI - Validation of higher-throughput high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry assays to conduct cytochrome P450s CYP2D6 and CYP3A4 enzyme inhibition studies in human liver microsomes SN - 0951-4198 PY - 2000///0320 KW - Atmospheric Pressure KW - Chromatography, High Pressure Liquid KW - methods KW - Cytochrome P-450 CYP2D6 KW - analysis KW - Cytochrome P-450 CYP2D6 Inhibitors KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 Enzyme Inhibitors KW - Cytochrome P-450 Enzyme System KW - Dextrorphan KW - chemistry KW - Drug Design KW - Drug Evaluation, Preclinical KW - Enzyme Inhibitors KW - Evaluation Studies as Topic KW - Humans KW - Hydroxytestosterones KW - In Vitro Techniques KW - Mass Spectrometry KW - Microsomes, Liver KW - enzymology KW - Mixed Function Oxygenases KW - Reproducibility of Results KW - Substrate Specificity N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/(SICI)1097-0231(20000229)14:4<207::AID-RCM863>3.0.CO;2-# ER -