Chu, I <br/><br/>
Validation of higher-throughput high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry assays to conduct cytochrome P450s CYP2D6 and CYP3A4 enzyme inhibition studies in human liver microsomes.  [electronic resource] 

 -  Rapid communications in mass spectrometry : RCM  2000 
 - 207-14 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0951-4198 
<br/><br/><label>Standard No.: </label>10.1002/(SICI)1097-0231(20000229)14:4<207::AID-RCM863>3.0.CO;2-#  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Atmospheric Pressure<br/>Chromatography, High Pressure Liquid--methods<br/>Cytochrome P-450 CYP2D6--analysis<br/>Cytochrome P-450 CYP2D6 Inhibitors<br/>Cytochrome P-450 CYP3A<br/>Cytochrome P-450 Enzyme Inhibitors<br/>Cytochrome P-450 Enzyme System--analysis<br/>Dextrorphan--chemistry<br/>Drug Design<br/>Drug Evaluation, Preclinical<br/>Enzyme Inhibitors--chemistry<br/>Evaluation Studies as Topic<br/>Humans<br/>Hydroxytestosterones--chemistry<br/>In Vitro Techniques<br/>Mass Spectrometry--methods<br/>Microsomes, Liver--enzymology<br/>Mixed Function Oxygenases--analysis<br/>Reproducibility of Results<br/>Substrate Specificity