Ichimura, K

Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities. [electronic resource] - Cancer research Jan 2000 - 417-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


Astrocytoma--genetics
Brain Neoplasms--genetics
Cell Cycle--genetics
DNA Mutational Analysis
Exons
G1 Phase
Gene Silencing
Genes, p53
Glioblastoma--genetics
Humans
Mutation
Nuclear Proteins
Proteins--genetics
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-mdm2
Proto-Oncogenes
S Phase
Sequence Deletion
Transcriptional Activation
Tumor Suppressor Protein p14ARF
Tumor Suppressor Protein p53--metabolism