TY  - GEN
AU  - Eckenberg,R
AU  - Rose,T
AU  - Moreau,J L
AU  - Weil,R
AU  - Gesbert,F
AU  - Dubois,S
AU  - Tello,D
AU  - Bossus,M
AU  - Gras,H
AU  - Tartar,A
AU  - Bertoglio,J
AU  - Chouaïb,S
AU  - Goldberg,M
AU  - Jacques,Y
AU  - Alzari,P M
AU  - Thèze,J
TI  - The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cells
SN  - 0022-1007
PY  - 2000///0418
KW  - Amino Acid Sequence
KW  - Animals
KW  - Binding Sites
KW  - CD8-Positive T-Lymphocytes
KW  - metabolism
KW  - Cell Line
KW  - Enzyme Activation
KW  - drug effects
KW  - Humans
KW  - Interferon-gamma
KW  - analysis
KW  - Interleukin-2
KW  - chemistry
KW  - Killer Cells, Lymphokine-Activated
KW  - Lymphocyte Activation
KW  - Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
KW  - Lymphocyte Subsets
KW  - Mice
KW  - Molecular Sequence Data
KW  - Monocytes
KW  - Peptide Fragments
KW  - Protein Folding
KW  - Receptors, Interleukin-2
KW  - agonists
KW  - Signal Transduction
KW  - src Homology Domains
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1084/jem.191.3.529
ER  -