TY  - GEN
AU  - Barnes,M J
AU  - Taylor,G A
AU  - Newell,D R
TI  - Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells
SN  - 0006-2952
PY  - 2000///0203
KW  - Adenine
KW  - biosynthesis
KW  - Antimetabolites, Antineoplastic
KW  - pharmacology
KW  - Child
KW  - Guanine
KW  - Humans
KW  - Inosine
KW  - metabolism
KW  - Leukemia
KW  - Methotrexate
KW  - Precursor Cell Lymphoblastic Leukemia-Lymphoma
KW  - Purines
KW  - Thymidine
KW  - Thymidylate Synthase
KW  - antagonists & inhibitors
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/s0006-2952(99)00320-2
ER  -