Barnes, M J <br/><br/>
Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells.  [electronic resource] 

 -  Biochemical pharmacology  Feb 2000 
 - 321-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-2952 
<br/><br/><label>Standard No.: </label>10.1016/s0006-2952(99)00320-2  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenine--biosynthesis<br/>Antimetabolites, Antineoplastic--pharmacology<br/>Child<br/>Guanine--biosynthesis<br/>Humans<br/>Inosine--metabolism<br/>Leukemia--metabolism<br/>Methotrexate--pharmacology<br/>Precursor Cell Lymphoblastic Leukemia-Lymphoma--metabolism<br/>Purines--biosynthesis<br/>Thymidine--metabolism<br/>Thymidylate Synthase--antagonists & inhibitors<br/>Tumor Cells, Cultured