TY  - GEN
AU  - Perloff,M D
AU  - von Moltke,L L
AU  - Court,M H
AU  - Kotegawa,T
AU  - Shader,R I
AU  - Greenblatt,D J
TI  - Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms
SN  - 0022-3565
PY  - 2000///0222
KW  - Animals
KW  - Antibodies
KW  - pharmacology
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Biotransformation
KW  - Blotting, Western
KW  - Chromatography, High Pressure Liquid
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - immunology
KW  - Dose-Response Relationship, Drug
KW  - Humans
KW  - Immunochemistry
KW  - In Vitro Techniques
KW  - Inhibitory Concentration 50
KW  - Ketoconazole
KW  - Mice
KW  - Microsomes, Liver
KW  - metabolism
KW  - Midazolam
KW  - pharmacokinetics
KW  - Mixed Function Oxygenases
KW  - Oxidoreductases, N-Demethylating
KW  - physiology
KW  - Protein Isoforms
KW  - Species Specificity
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - Triazolam
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
ER  -