Cummings, C J <br/><br/>
Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.  [electronic resource] 

 -  Neuron  Dec 1999 
 - 879-92 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0896-6273 
<br/><br/><label>Standard No.: </label>10.1016/s0896-6273(00)81035-1  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Ataxin-1<br/>Ataxins<br/>Cell Nucleus--genetics<br/>Cells, Cultured<br/>Cysteine Endopeptidases--metabolism<br/>Fluorescent Antibody Technique<br/>HeLa Cells<br/>Humans<br/>Immunoblotting<br/>Immunohistochemistry<br/>Inclusion Bodies--genetics<br/>Ligases--deficiency<br/>Mice<br/>Mice, Knockout<br/>Microscopy, Confocal<br/>Multienzyme Complexes--metabolism<br/>Mutation--physiology<br/>Nerve Tissue Proteins--biosynthesis<br/>Nuclear Proteins--biosynthesis<br/>Peptides--toxicity<br/>Phenotype<br/>Plasmids--genetics<br/>Proteasome Endopeptidase Complex<br/>Purkinje Cells--metabolism<br/>Spinocerebellar Degenerations--genetics<br/>Ubiquitin-Protein Ligases<br/>Ubiquitins--genetics