TY - GEN AU - Brando,C AU - Marcinkiewicz,C AU - Goldman,B AU - McLane,M A AU - Niewiarowski,S TI - EC3, a heterodimeric disintegrin from Echis carinatus, inhibits human and murine alpha4 integrin and attenuates lymphocyte infiltration of Langerhans islets in pancreas and salivary glands in nonobese diabetic mice SN - 0006-291X PY - 2000///0208 KW - Amino Acid Sequence KW - Animals KW - Antigens, CD KW - drug effects KW - Cell Adhesion KW - Diabetes Mellitus, Type 1 KW - immunology KW - Disintegrins KW - chemistry KW - Humans KW - Integrin alpha4 KW - Intercellular Signaling Peptides and Proteins KW - Islets of Langerhans KW - Jurkat Cells KW - Lymphocytes KW - Mice KW - Mice, Inbred NOD KW - Molecular Sequence Data KW - Peptides KW - Salivary Glands KW - Sequence Alignment KW - Sequence Homology, Amino Acid KW - Spleen KW - Tumor Cells, Cultured KW - Viper Venoms N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1006/bbrc.1999.1897 ER -