LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. [electronic resource]
- FEBS letters Dec 1999
- 365-70 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0014-5793
10.1016/s0014-5793(99)01662-2 doi
Animals Cell Line DNA-Binding Proteins--metabolism Gene Expression Regulation--drug effects Genes, Suppressor Humans Interleukin-6--antagonists & inhibitors Kupffer Cells--drug effects Lipopolysaccharides--pharmacology Liver--cytology Macrophages--drug effects Male Mice Mitogen-Activated Protein Kinases--antagonists & inhibitors Rats Rats, Wistar STAT3 Transcription Factor Signal Transduction--drug effects Trans-Activators--metabolism Tumor Cells, Cultured Tumor Necrosis Factor-alpha--pharmacology p38 Mitogen-Activated Protein Kinases