Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Jan 2000
- 13-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-1767
10.4049/jimmunol.164.1.13 doi
Animals CHO Cells Cells, Cultured Chaperonin 60--physiology Chlamydia--immunology Cricetinae Cytokines--biosynthesis Endotoxins--physiology Enzyme Activation--immunology Genes, Reporter--immunology Humans Immunity, Innate Lipopolysaccharide Receptors--metabolism Macrophage Activation--immunology Macrophages--immunology Mitogen-Activated Protein Kinases--metabolism Monocytes--immunology NF-kappa B--genetics Signal Transduction--immunology Tumor Cells, Cultured p38 Mitogen-Activated Protein Kinases