TY  - GEN
AU  - White,H S
AU  - McCabe,R T
AU  - Armstrong,H
AU  - Donevan,S D
AU  - Cruz,L J
AU  - Abogadie,F C
AU  - Torres,J
AU  - Rivier,J E
AU  - Paarmann,I
AU  - Hollmann,M
AU  - Olivera,B M
TI  - In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus
SN  - 0022-3565
PY  - 2000///0127
KW  - Animals
KW  - Anticonvulsants
KW  - therapeutic use
KW  - Behavior, Animal
KW  - drug effects
KW  - Binding, Competitive
KW  - Cerebral Cortex
KW  - Conotoxins
KW  - chemical synthesis
KW  - Dizocilpine Maleate
KW  - Dose-Response Relationship, Drug
KW  - Drug Interactions
KW  - Electroshock
KW  - Evoked Potentials
KW  - Female
KW  - Glutamic Acid
KW  - pharmacology
KW  - In Vitro Techniques
KW  - Kainic Acid
KW  - Male
KW  - Mice
KW  - Mollusk Venoms
KW  - chemistry
KW  - Oocytes
KW  - physiology
KW  - Pentylenetetrazole
KW  - toxicity
KW  - Piperidines
KW  - Receptors, AMPA
KW  - classification
KW  - Receptors, N-Methyl-D-Aspartate
KW  - antagonists & inhibitors
KW  - Recombinant Proteins
KW  - Seizures
KW  - drug therapy
KW  - Sound
KW  - adverse effects
KW  - Xenopus
KW  - gamma-Aminobutyric Acid
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -