White, H S

In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jan 2000 - 425-32 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-3565


Animals
Anticonvulsants--therapeutic use
Behavior, Animal--drug effects
Binding, Competitive
Cerebral Cortex--drug effects
Conotoxins--chemical synthesis
Dizocilpine Maleate--therapeutic use
Dose-Response Relationship, Drug
Drug Interactions
Electroshock
Evoked Potentials--drug effects
Female
Glutamic Acid--pharmacology
In Vitro Techniques
Kainic Acid--pharmacology
Male
Mice
Mollusk Venoms--chemistry
Oocytes--physiology
Pentylenetetrazole--toxicity
Piperidines--therapeutic use
Receptors, AMPA--classification
Receptors, N-Methyl-D-Aspartate--antagonists & inhibitors
Recombinant Proteins
Seizures--drug therapy
Sound--adverse effects
Xenopus--physiology
gamma-Aminobutyric Acid--pharmacology