Matsui, K <br/><br/>
Correlation of the intrinsic clearance of donepezil (Aricept) between in vivo and in vitro studies in rat, dog and human.  [electronic resource] 

 -  Xenobiotica; the fate of foreign compounds in biological systems  Nov 1999 
 - 1059-72 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>0049-8254 
<br/><br/><label>Standard No.: </label>10.1080/004982599237958  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Algorithms<br/>Animals<br/>Biotransformation<br/>Blood Proteins--metabolism<br/>Cholinesterase Inhibitors--administration & dosage<br/>Chromatography, High Pressure Liquid<br/>Chromatography, Thin Layer<br/>Dogs<br/>Donepezil<br/>Female<br/>Humans<br/>In Vitro Techniques<br/>Indans--administration & dosage<br/>Injections, Intravenous<br/>Kinetics<br/>Male<br/>Microsomes, Liver--metabolism<br/>Piperidines--administration & dosage<br/>Protein Binding<br/>Rats<br/>Rats, Sprague-Dawley<br/>Species Specificity