E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. [electronic resource]
- Journal of virology Jan 2000
- 193-202 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-538X
10.1128/jvi.74.1.193-202.2000 doi
Adenovirus E1B Proteins--physiology Base Sequence Cell Nucleus--metabolism Cytoplasm--metabolism DNA Primers DNA-Binding Proteins--metabolism Genes, Tumor Suppressor Humans Nuclear Proteins--metabolism Open Reading Frames Phosphoproteins Trans-Activators Transcription Factors Transcription, Genetic Tumor Protein p73 Tumor Suppressor Protein p53--antagonists & inhibitors Tumor Suppressor Proteins