TY  - GEN
AU  - Toretsky,J A
AU  - Thakar,M
AU  - Eskenazi,A E
AU  - Frantz,C N
TI  - Phosphoinositide 3-hydroxide kinase blockade enhances apoptosis in the Ewing's sarcoma family of tumors
SN  - 0008-5472
PY  - 1999///1214
KW  - Androstadienes
KW  - pharmacology
KW  - Antineoplastic Agents
KW  - antagonists & inhibitors
KW  - Apoptosis
KW  - genetics
KW  - Caspase 3
KW  - Caspases
KW  - metabolism
KW  - Cell Transformation, Neoplastic
KW  - chemically induced
KW  - DNA Fragmentation
KW  - Doxorubicin
KW  - Enzyme Activation
KW  - drug effects
KW  - Enzyme Inhibitors
KW  - Humans
KW  - In Situ Nick-End Labeling
KW  - Insulin-Like Growth Factor I
KW  - Neoplasm Proteins
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - physiology
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - Receptor, IGF Type 1
KW  - Sarcoma, Ewing
KW  - enzymology
KW  - Tumor Cells, Cultured
KW  - Wortmannin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ER  -