Lagu, B <br/><br/>
Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 3. Approaches to eliminate opioid agonist metabolites by using substituted phenylpiperazine side chains.  [electronic resource] 

 -  Journal of medicinal chemistry  Nov 1999 
 - 4794-803 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm990202+  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adrenergic alpha-Antagonists--chemical synthesis<br/>Animals<br/>Binding, Competitive<br/>Biological Availability<br/>Dogs<br/>Drug Design<br/>GTP-Binding Proteins--metabolism<br/>Half-Life<br/>Humans<br/>In Vitro Techniques<br/>Male<br/>Piperazines--chemical synthesis<br/>Prostate--metabolism<br/>Pyrimidinones--chemical synthesis<br/>Rats<br/>Receptors, Adrenergic, alpha-1--metabolism<br/>Receptors, Opioid, mu--agonists<br/>Recombinant Proteins--metabolism<br/>Stereoisomerism<br/>Structure-Activity Relationship