TY  - GEN
AU  - Reszka,A A
AU  - Halasy-Nagy,J M
AU  - Masarachia,P J
AU  - Rodan,G A
TI  - Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase
SN  - 0021-9258
PY  - 2000///0203
KW  - Alendronate
KW  - pharmacology
KW  - Animals
KW  - Apoptosis
KW  - Calcium Channel Blockers
KW  - Caspase Inhibitors
KW  - Caspases
KW  - metabolism
KW  - Clodronic Acid
KW  - Diphosphonates
KW  - Diterpenes
KW  - Enzyme Activation
KW  - drug effects
KW  - Etidronic Acid
KW  - analogs & derivatives
KW  - MAP Kinase Kinase Kinases
KW  - Macrophage Colony-Stimulating Factor
KW  - Male
KW  - Mevalonic Acid
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Osteoclasts
KW  - Protein Prenylation
KW  - Protein Serine-Threonine Kinases
KW  - Risedronic Acid
KW  - Signal Transduction
KW  - Staurosporine
KW  - Time Factors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1074/jbc.274.49.34967
ER  -