Fiorani, P <br/><br/>
Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.  [electronic resource] 

 -  Molecular pharmacology  Dec 1999 
 - 1105-15 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0026-895X 
<br/><br/><label>Standard No.: </label>10.1124/mol.56.6.1105  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alanine--genetics<br/>Amino Acid Substitution<br/>Camptothecin--pharmacology<br/>Catalysis<br/>DNA--drug effects<br/>DNA Topoisomerases, Type I--chemistry<br/>Drug Resistance<br/>Enzyme Inhibitors--pharmacology<br/>Enzyme Stability<br/>Glycine--genetics<br/>Humans<br/>Models, Molecular<br/>Mutation<br/>Protein Conformation<br/>Protein Structure, Tertiary<br/>Saccharomyces cerevisiae--genetics<br/>Threonine--genetics<br/>Topoisomerase I Inhibitors<br/>Transfection