Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells. [electronic resource]
- The Journal of biological chemistry Nov 1999
- 33637-43 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.274.47.33637 doi
Alleles Animals Base Sequence Cell Division--physiology Cell Line Colonic Neoplasms--metabolism DNA Primers DNA-Binding Proteins--genetics Gene Silencing Humans Smad3 Protein Smad4 Protein Trans-Activators--genetics Transforming Growth Factor beta--antagonists & inhibitors Tumor Cells, Cultured ras Proteins--metabolism