TY - GEN AU - Hansson,L O AU - Widersten,M AU - Mannervik,B TI - An approach to optimizing the active site in a glutathione transferase by evolution in vitro SN - 0264-6021 PY - 2000///0127 KW - Amino Acid Substitution KW - Base Sequence KW - Catalytic Domain KW - genetics KW - DNA Primers KW - Dinitrochlorobenzene KW - metabolism KW - Directed Molecular Evolution KW - Genetic Variation KW - Glutathione Transferase KW - chemistry KW - Humans KW - In Vitro Techniques KW - Kinetics KW - Models, Molecular KW - Mutagenesis, Site-Directed KW - Protein Structure, Secondary KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -