TY  - GEN
AU  - Rani,M R
AU  - Leaman,D W
AU  - Han,Y
AU  - Leung,S
AU  - Croze,E
AU  - Fish,E N
AU  - Wolfman,A
AU  - Ransohoff,R M
TI  - Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase
SN  - 0021-9258
PY  - 1999///1213
KW  - Catalysis
KW  - DNA-Binding Proteins
KW  - metabolism
KW  - Enzyme Activation
KW  - Humans
KW  - Interferon-beta
KW  - Membrane Proteins
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphorylation
KW  - Protein-Tyrosine Kinases
KW  - Proteins
KW  - Receptor, Interferon alpha-beta
KW  - Receptors, Interferon
KW  - STAT3 Transcription Factor
KW  - Signal Transduction
KW  - TYK2 Kinase
KW  - Trans-Activators
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.274.45.32507
ER  -