TY - GEN AU - Owada,K AU - Sanjo,N AU - Kobayashi,T AU - Mizusawa,H AU - Muramatsu,H AU - Muramatsu,T AU - Michikawa,M TI - Midkine inhibits caspase-dependent apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons SN - 0022-3042 PY - 1999///1105 KW - Androstadienes KW - pharmacology KW - Animals KW - Apoptosis KW - drug effects KW - Carrier Proteins KW - Caspase 3 KW - Caspases KW - Cells, Cultured KW - Cerebral Cortex KW - Culture Media, Serum-Free KW - Cytokines KW - Embryo, Mammalian KW - Enzyme Activation KW - Enzyme Inhibitors KW - Flavonoids KW - In Situ Nick-End Labeling KW - Mice KW - Midkine KW - Mitogen-Activated Protein Kinase 1 KW - metabolism KW - Mitogen-Activated Protein Kinase 3 KW - Mitogen-Activated Protein Kinases KW - antagonists & inhibitors KW - Neurons KW - enzymology KW - Phosphatidylinositol 3-Kinases KW - Phosphoinositide-3 Kinase Inhibitors KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Recombinant Proteins KW - Wortmannin N1 - Publication Type: Journal Article ER -