TY - GEN AU - Burger,C AU - Carrondo,M J AU - Cruz,H AU - Cuffe,M AU - Dias,E AU - Griffiths,J B AU - Hayes,K AU - Hauser,H AU - Looby,D AU - Mielke,C AU - Moreira,J L AU - Rieke,E AU - Savage,A V AU - Stacey,G N AU - Welge,T TI - An integrated strategy for the process development of a recombinant antibody-cytokine fusion protein expressed in BHK cells SN - 0175-7598 PY - 1999///1215 KW - Animals KW - Antineoplastic Agents KW - isolation & purification KW - Bioreactors KW - Carbohydrate Sequence KW - Cell Line KW - Chromatography, High Pressure Liquid KW - Cricetinae KW - Culture Media, Serum-Free KW - Drug Screening Assays, Antitumor KW - ErbB Receptors KW - immunology KW - Genes KW - genetics KW - Genes, Synthetic KW - Genetic Vectors KW - Glycosylation KW - Immunoglobulin G KW - Kidney KW - Mesocricetus KW - Molecular Sequence Data KW - Oligosaccharides KW - chemistry KW - Protein Processing, Post-Translational KW - Recombinant Fusion Proteins KW - biosynthesis KW - Selection, Genetic KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Tumor Cells, Cultured KW - drug effects KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s002530051530 ER -