Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms. [electronic resource]
- British journal of pharmacology Sep 1999
- 337-44 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0007-1188
10.1038/sj.bjp.0702782 doi
Animals Blotting, Southern Cell Line Cyclosporine--pharmacology Depression, Chemical Enzyme Inhibitors--pharmacology Immunosuppressive Agents--pharmacology Interferon-gamma--pharmacology Lipopolysaccharides--pharmacology Macrophages--drug effects Male Mice Muscle, Smooth, Vascular--drug effects Nitric Oxide Synthase--antagonists & inhibitors Nitric Oxide Synthase Type II Nitrites--metabolism RNA, Messenger--biosynthesis Rats Rats, Sprague-Dawley Recombinant Proteins Reverse Transcriptase Polymerase Chain Reaction Tacrolimus--pharmacology