O'Byrne, K J <br/><br/>
A phase II study of the modulation of 5-fluorouracil and folinic acid with high-dose infusional hydroxyurea in metastatic colorectal carcinoma.  [electronic resource] 

 -  Annals of oncology : official journal of the European Society for Medical Oncology  Aug 1999 
 - 981-3 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0923-7534 
<br/><br/><label>Standard No.: </label>10.1023/a:1008330302535  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenocarcinoma--drug therapy<br/>Adult<br/>Aged<br/>Antineoplastic Combined Chemotherapy Protocols--adverse effects<br/>Colorectal Neoplasms--drug therapy<br/>Disease-Free Survival<br/>Dose-Response Relationship, Drug<br/>Female<br/>Fluorouracil--administration & dosage<br/>Humans<br/>Hydroxyurea--administration & dosage<br/>Infusions, Intravenous<br/>Leucovorin--administration & dosage<br/>Male<br/>Middle Aged<br/>Nucleic Acid Synthesis Inhibitors--administration & dosage<br/>Prognosis<br/>Survival Rate<br/>Treatment Outcome