Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. [electronic resource]
- Science (New York, N.Y.) Oct 1999
- 113-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0036-8075
10.1126/science.286.5437.113 doi
Amino Acid Sequence Animals Catalysis Cytoplasmic Granules--enzymology Escherichia coli--growth & development Escherichia coli Infections--immunology Female Humans Immunity, Innate Immunity, Mucosal Intestinal Mucosa--enzymology Intestine, Small--enzymology Male Matrix Metalloproteinase 7 Metalloendopeptidases--genetics Mice Molecular Sequence Data Paneth Cells--enzymology Protein Precursors--genetics Recombinant Fusion Proteins--metabolism Salmonella typhimurium--growth & development Tissue Extracts--pharmacology