EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1. [electronic resource]
- Oncogene Sep 1999
- 4920-9 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0950-9232
10.1038/sj.onc.1202874 doi
Adenomatous Polyposis Coli Protein Amino Acid Sequence B-Lymphocytes--enzymology Bone Marrow Cells--metabolism Cell Line Cell Transformation, Neoplastic--genetics Cytoskeletal Proteins--chemistry Expressed Sequence Tags Fetus--metabolism Gene Expression Regulation, Neoplastic Homeodomain Proteins--genetics Humans Molecular Sequence Data Neoplasm Proteins--analysis Oncogene Proteins, Fusion--genetics Organ Specificity Phosphotyrosine--metabolism Precursor B-Cell Lymphoblastic Leukemia-Lymphoma--enzymology Protein-Tyrosine Kinases--chemistry RNA, Messenger--analysis Sequence Homology, Amino Acid Signal Transduction Stem Cells--enzymology Transcriptional Activation Translocation, Genetic--genetics