Growth stimulation versus induction of cell quiescence by hydrogen peroxide in prostate tumor spheroids is encoded by the duration of the Ca(2+) response. [electronic resource]
- The Journal of biological chemistry Sep 1999
- 27759-67 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.274.39.27759 doi
Cell Cycle Proteins Cell Division--drug effects Cyclin-Dependent Kinase Inhibitor p27 Cyclin-Dependent Kinases--antagonists & inhibitors Drug Resistance, Multiple Enzyme Inhibitors--metabolism Gene Expression Regulation, Neoplastic--drug effects Genes, fos Humans Hydrogen Peroxide--pharmacology JNK Mitogen-Activated Protein Kinases Kinetics MAP Kinase Kinase 1 MAP Kinase Kinase 2 Male Microtubule-Associated Proteins--genetics Mitogen-Activated Protein Kinase 1--metabolism Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinase Kinases--metabolism Mitogen-Activated Protein Kinases--metabolism Prostatic Neoplasms--pathology Protein Serine-Threonine Kinases Protein-Tyrosine Kinases--metabolism Proto-Oncogene Proteins c-fos--biosynthesis Tumor Cells, Cultured Tumor Suppressor Proteins