Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole. [electronic resource]
- Mutagenesis Sep 1999
- 513-20 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0267-8357
10.1093/mutage/14.5.513 doi
Adult Antineoplastic Agents--pharmacology Apoptosis--drug effects Cell Survival--drug effects Cells, Cultured Demecolcine--pharmacology Dose-Response Relationship, Drug Gene Expression Humans In Situ Nick-End Labeling K562 Cells Leukemia--genetics Lymphocytes--cytology Nocodazole--pharmacology Phytohemagglutinins--pharmacology Polyploidy Spindle Apparatus--drug effects Time Factors Tumor Cells, Cultured Tumor Suppressor Protein p53--genetics