3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats. [electronic resource]
- Gastroenterology Sep 1999
- 678-87 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0016-5085
10.1016/s0016-5085(99)70462-2 doi
ATP Binding Cassette Transporter, Subfamily B--biosynthesis ATP-Binding Cassette Transporters--biosynthesis Animals Anticholesteremic Agents--pharmacology Bile--metabolism Blotting, Western Cholesterol--biosynthesis Diosgenin--pharmacology Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology Immunohistochemistry Liver--drug effects Male Phospholipids--biosynthesis Pravastatin--pharmacology RNA, Messenger--analysis Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction Simvastatin--pharmacology ATP-Binding Cassette Sub-Family B Member 4