Shimizu, A

The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. [electronic resource] - Cancer research Aug 1999 - 3719-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


3T3 Cells
Animals
Antineoplastic Agents--pharmacology
Becaplermin
Benzamides
Cell Transformation, Neoplastic--genetics
Cosmids
Dermatofibrosarcoma--genetics
Enzyme Inhibitors--pharmacology
Imatinib Mesylate
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Proteins--antagonists & inhibitors
Oncogene Proteins, Fusion--genetics
Piperazines--pharmacology
Platelet-Derived Growth Factor--biosynthesis
Proto-Oncogene Proteins c-sis
Pyrimidines--pharmacology
Receptor Protein-Tyrosine Kinases--antagonists & inhibitors
Receptor, Platelet-Derived Growth Factor beta
Receptors, Platelet-Derived Growth Factor--drug effects
Skin Neoplasms--genetics