Qin, X

Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT. [electronic resource] - Oncogene Jul 1999 - 4394-400 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0950-9232

10.1038/sj.onc.1202798 doi


Adenosine Triphosphatases
Animals
Carcinogens
DNA Repair Enzymes
DNA-Binding Proteins
Genetic Predisposition to Disease
Humans
Hypersensitivity
Lymphoma--metabolism
Methylnitrosourea
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Mismatch Repair Endonuclease PMS2
Models, Biological
O(6)-Methylguanine-DNA Methyltransferase--metabolism
Polymerase Chain Reaction
Proteins--genetics
Thymus Neoplasms--chemically induced
Time Factors