TY - GEN AU - Rousseau,D AU - Cannella,D AU - Boulaire,J AU - Fitzgerald,P AU - Fotedar,A AU - Fotedar,R TI - Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway SN - 0950-9232 PY - 1999///0813 KW - 3T3 Cells KW - Acetylcysteine KW - analogs & derivatives KW - Animals KW - CDC2-CDC28 Kinases KW - Cyclin-Dependent Kinase 2 KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclin-Dependent Kinases KW - immunology KW - Cyclins KW - genetics KW - Cycloheximide KW - pharmacology KW - Cysteine Endopeptidases KW - metabolism KW - Cysteine Proteinase Inhibitors KW - Gene Deletion KW - Gene Expression Regulation, Neoplastic KW - Growth Inhibitors KW - Hemagglutinins KW - Humans KW - Leupeptins KW - Mice KW - Models, Genetic KW - Multienzyme Complexes KW - Mutagenesis KW - Osteosarcoma KW - Proliferating Cell Nuclear Antigen KW - Proteasome Endopeptidase Complex KW - Protein Serine-Threonine Kinases KW - Protein Synthesis Inhibitors KW - Time Factors KW - Transfection KW - Tumor Cells, Cultured KW - Ubiquitins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1038/sj.onc.1202686 ER -