IkappaBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death. [electronic resource]
- American journal of respiratory cell and molecular biology Aug 1999
- 238-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
1044-1549
10.1165/ajrcmb.21.2.3470 doi
Adenoviridae--genetics Carcinoma, Squamous Cell--metabolism Cell Death Cell Survival DNA-Binding Proteins--genetics Dose-Response Relationship, Drug Gene Transfer Techniques Genetic Vectors Humans I-kappa B Proteins NF-KappaB Inhibitor alpha NF-kappa B--metabolism Transduction, Genetic Transgenes Tumor Cells, Cultured Tumor Necrosis Factor-alpha--metabolism