TY - GEN AU - Beltinger,C AU - Fulda,S AU - Kammertoens,T AU - Meyer,E AU - Uckert,W AU - Debatin,K M TI - Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases SN - 0027-8424 PY - 1999///0823 KW - Adaptor Proteins, Signal Transducing KW - Antiviral Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - Brefeldin A KW - Carrier Proteins KW - metabolism KW - Caspases KW - Enzyme Activation KW - Fas Ligand Protein KW - Fas-Associated Death Domain Protein KW - Ganciclovir KW - Genetic Therapy KW - methods KW - Humans KW - Membrane Glycoproteins KW - Protease Inhibitors KW - Receptors, Tumor Necrosis Factor KW - Simplexvirus KW - enzymology KW - TNF-Related Apoptosis-Inducing Ligand KW - Thymidine Kinase KW - Transfection KW - Tumor Cells, Cultured KW - Tumor Necrosis Factor-alpha KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article UR - https://doi.org/10.1073/pnas.96.15.8699 ER -