TY  - GEN
AU  - Chan,C C
AU  - Boyce,S
AU  - Brideau,C
AU  - Charleson,S
AU  - Cromlish,W
AU  - Ethier,D
AU  - Evans,J
AU  - Ford-Hutchinson,A W
AU  - Forrest,M J
AU  - Gauthier,J Y
AU  - Gordon,R
AU  - Gresser,M
AU  - Guay,J
AU  - Kargman,S
AU  - Kennedy,B
AU  - Leblanc,Y
AU  - Leger,S
AU  - Mancini,J
AU  - O'Neill,G P
AU  - Ouellet,M
AU  - Patrick,D
AU  - Percival,M D
AU  - Perrier,H
AU  - Prasit,P
AU  - Rodger,I
TI  - Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles
SN  - 0022-3565
PY  - 1999///0818
KW  - 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
KW  - metabolism
KW  - Animals
KW  - Arachidonate 15-Lipoxygenase
KW  - Arachidonic Acid
KW  - Arthritis, Experimental
KW  - blood
KW  - Blood Platelets
KW  - drug effects
KW  - COS Cells
KW  - Cell Line
KW  - Cricetinae
KW  - Cyclooxygenase 2
KW  - Cyclooxygenase 2 Inhibitors
KW  - Cyclooxygenase Inhibitors
KW  - pharmacology
KW  - Digestive System
KW  - Dogs
KW  - Edema
KW  - chemically induced
KW  - Female
KW  - Humans
KW  - Hyperalgesia
KW  - In Vitro Techniques
KW  - Isoenzymes
KW  - Lactones
KW  - Leukotriene B4
KW  - biosynthesis
KW  - Male
KW  - Membrane Proteins
KW  - Microsomes
KW  - Prostaglandin-Endoperoxide Synthases
KW  - Rats
KW  - Rats, Inbred Lew
KW  - Saimiri
KW  - Sulfones
N1  - Publication Type: Journal Article
ER  -