Lamb, D C

Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents. [electronic resource] - Yeast (Chichester, England) Jun 1999 - 755-63 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0749-503X

10.1002/(SICI)1097-0061(19990630)15:9<755::AID-YEA417>3.0.CO;2-8 doi


Antifungal Agents--chemistry
Binding Sites
Candida albicans--enzymology
Carbon Monoxide--metabolism
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--chemistry
Formates--metabolism
Humans
Inhibitory Concentration 50
Itraconazole--chemistry
Ketoconazole--chemistry
Kinetics
Ligands
Oxidoreductases--antagonists & inhibitors
Recombinant Proteins--antagonists & inhibitors
Spectrum Analysis
Sterol 14-Demethylase
Titrimetry