Tanaka, T

High incidence of allelic loss on chromosome 5 and inactivation of p15INK4B and p16INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats. [electronic resource] - Oncogene Jun 1999 - 3793-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0950-9232

10.1038/sj.onc.1202707 doi


Animals
Base Sequence
Blotting, Southern
Carcinogens--toxicity
Carcinoma, Renal Cell--chemically induced
Carrier Proteins--genetics
Cell Cycle Proteins
Chromosomes, Human, Pair 5--genetics
CpG Islands
Crosses, Genetic
Cyclin-Dependent Kinase Inhibitor p15
Cyclin-Dependent Kinase Inhibitor p16
DNA Methylation
DNA, Neoplasm--genetics
Ferric Compounds--toxicity
Gene Deletion
Genes, Tumor Suppressor
Genes, p16
Humans
Kidney Neoplasms--chemically induced
Kidney Tubules, Proximal--drug effects
Loss of Heterozygosity
Microsatellite Repeats
Molecular Sequence Data
Nitrilotriacetic Acid--analogs & derivatives
Oxidative Stress
Point Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Rats
Rats, Wistar
Tumor Suppressor Proteins