Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis. [electronic resource]
- Molecular pharmacology Jul 1999
- 68-76 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0026-895X
Animals Biological Transport Carrier Proteins--genetics Drug Resistance, Neoplasm Folic Acid Antagonists--pharmacology Leukemia L1210 Membrane Proteins--chemistry Membrane Transport Proteins Methotrexate--pharmacology Mice Mutagenesis Reduced Folate Carrier Protein Tumor Cells, Cultured